Long-term effects of organ-preserving treatment of benign tumors

Abstract

DOI: 10.52705/2788-6190-2023-02-5
УДК 618.1-089.87

Hysterectomy is one of the most common surgical procedures performed on women worldwide.Therefore, understanding the relationship between hysterectomy and ovarian neoplasia riskis crucial to inform the debate about the relative merits of prophylactic ovarian removal duringhysterectomy.

The objective: to investigate the prevalence of benign and malignant ovarian tumors in patientsundergoing hysterectomy in connection with benign uterine diseases and to study the relationshipbetween age at surgery and the incidence of ovarian tumors in these patients.

Materials and methods. Patients were divided into two groups depending on their age at thetime of surgery: Group 1 included patients under 45 years of age (n=162), and Group 2 includedpatients over 45 years of age (n=107).

Results. The mean age in group 1 was 38,48±4,42 years, while in group 2 – 51,18±3,71 years.The data showed that 8.6% of patients in the younger group had benign tumors, while in theolder group – 5,6%. However, this difference was not statistically significant (p=0,478). Theprevalence of malignant tumors was significantly higher in patients in the older group comparedto the younger group (5,2% vs. 2,5%; p=0,022).Belonging to the observation group (≤45 years or >45 years) showed a statistically significantassociation with the prevalence of malignant tumors, as the odds ratio was 4,072 (95% CI: 1,243–13,342), and the p value was 0,020. This indicates that patients aged >45 years have a higher riskof developing malignant tumors compared to patients aged ≤45 years.

Conclusions. Patients aged >45 years who have undergone hysterectomy without ovariectomyhave a higher incidence of ovarian malignancy compared to patients aged ≤45 years.