Features of endocrinology status at acne for the women of early reproductive age

Abstract

DOI: 10.52705/2788-6190-2024-03.1-09

УДК 618.17/.5-036:616.53-002

The objective: to learn endocrinology aspects acne for the women of early reproductive age.
Materials and methods. As a result of screening inspection in research 50 patients entered
from acne different degree of severity. All patients produced complaints on acne in the area of
person, and 10 women (20,0%) also and in the area of breasts and back. Rashes, as a rule, were
not accompanied by the subjective feelings, after a liquid exception, when separate elements
were sickly at palpation. In addition, 39 patients (78,0%) marked the enhanceable facial skin
greasiness and scalp. Age of the investigated patients ranges from 18 to 25 years.
To the complex of the conducted researches clinical, laboratory, instrumental and statistical
methods were included. Determination in plasma of blood of albuminous (follicle-stimulating
hormone, luteinizing hormone) and steroid hormones (estradiol, testosterone, progesterone
and dehydroepiandrosterone sulfate) was conducted by radioimmunological methods in the
first phase of menstrual cycle on 5-8 day to treatment and in 6 months from the beginning of
research.

Results. Changes of hormonal type in blood of patients from acne allowed to establish
the phenomenon of hyperandrogenism, however much the analysis of changes of level of
hormones presents possible with authenticity to define the form of hyperandrogenic changes.
Exact information in relation to the exposure of predominating role of ovaries, adrenal glands
or hypothalamus, and also possibility of presence of different forms of hyperandrogenism can
be got only at the analysis of steroid type of urine, which was conducted before the beginning
of treatment to the patients for the rational selection of system therapy with the use of hormonal
preparations.
Conclusions. The results of the conducted researches testify that findings must be taken into
account at development of algorithm of diagnostic and treatment-and-prophylactic measures,
especially directed hormonal correction.