Diagnostic role of biophysical type of fetus and results of laboratory research of amniotic liquid at placenta disfunction

Abstract

DOI: 10.52705/2788-6190-2024-03.1-05
UDC 618.232:618.29:618.33:618.346-008.8-076/.078:618.2/.5-036.1

Research purpose. To learn the diagnostic value of biophysical type of fetus and laboratory research of amniotic liquid at physiology and pathological motion of pregnancy and births.

Materials and methods. Under our supervision in clinical terms was 142 puerperas which acted on births to maternity establishments of different level. All the inspected acted with beginning of childbirth. From an incurrence there were eliminated puerperas with a multifetation, pelvic fetal presentation, anomalies of development of fetus and antenatal death of fetus. Most inspected was in active reproductive age. Middle age of inspected made 24,9±0,3 year. From the incurrence of inspected almost half (48,6%) were primipara, the last were multiparous. From the incurrence of women which acted on births, give birth great majority in the term of gestation of 38-41 week (59,9%). Births which were late took place in 19,7% women, and in the last 20,4% women pregnancy made off premature births in terms of gestation 22-37 weeks (19,8%). 

Results. Intercommunication of amount of amniotic fluid with the parameters of cardiac activity of fetus and blood stream in an uterine artery and artery umbilical cord was obvious. Resistance of blood stream in these vessels was increased as far as diminishing of amount of amniotic liquid. The term of births, amount of amniotic liquid and parameters of cardiotocogram and doppler, in births is associate. The study of hormonal status of amniotic liquid rotined in births, that content of estradiol during a childbirth had hesitated within the limits of 30-180 ng/ml. Found out a reliable difference between maintenance of this hormone in a amniotic liquid at birth of boys and girls. At birth of girls the index of estradiol arrived at 21,4±2,3 ng/ml, while at birth of boys a middle index of estradiol was at the level of 16,5±2,3 ng/ml. Although found out a difference and did not carry reliable character (р>0,05), this fact specifies on participating of fetus in making of amniotic liquid. Meantime, level of estradiol in a amniotic liquid at birth of boys and girls identically for certain rose at presence of obstetric pathology, such as a weakness of childbirth in combination with fetal distress (p < 0,05).

Conclusion. The results of the conducted researches rotined that took place intercommunication between the basic parameters of biophysical type of fetus: echographic, cardiotocographic and doppler from one side, and from other - with the results of biochemical and hormonal research of amniotic liquid. The got results it is possible to draw on at development of tactic of conduct of pregnancy and births for women with a high perinatal risk, especially at the change of volume of amniotic liquid.