The women of postmenopausal age have features of hyperplastic processes of endometrium

Abstract

DOI: 10.52705/2788-6190-2024-03.1-13
UDC 618.14-002-007.61:618.173-071.1

The objective: study clinical-and-anamnestic features of hyperplastic processes of endometrium
for the women of postmenopausal age.
Materials and methods. 90 women were inspected with hyperplasia of endometrium in
postmenopause (basic group). Distributing of patients a morphological form served as a criterion
on groups. Among inspected glandular hyperplasia of endometrium was diagnosed in 32,2%
patients, in 45,6% are endometrial polyps, in 22,2% is adenomatous hyperplasia of endometrium.
A control group was made by 30 patients in postmenopause without hyperplasia of endometrium.
Results. Most women in research (76,7%) suffered a climacteric syndrome in the period of transition
of menopause (p<0,01). In 59,6% from them those or other displays of climacteric syndrome
were saved in a postmenopausal period. Among the clinical displays of climacteric syndrome in
postmenopause it is possible to select psycho-emotional, vasculomotor, urogenital disorders, and
also late variable violations. Patients which suffer a climacteric syndrome produced complaints
about hot waves, increased sweating, suppression of moods, «horripilation», chill, head pains,
confused, nausea. Complaint about the rush of heat and increased sweating was produced by
32,2% women with ferrous hyperplasia of endometrium, 52,5% patient with the endometrial polyps
and 18,6% inspected from a sub-group with adenomatous hyperplasia of endometrium.
Psycho-emotional climacteric violations appeared a neurosis-like syndrome: emotional lability,
suppression of moods, dysphoria, violation of cognitive processes, sleep and memory. A tearfulness
and crabbiness is marked for every second woman in research (50,0%); sleep disturbance – in
66,7%; confused, nausea and other vestibular symptoms – at the every third (33,3%). In the
sub-group of women with adenomatous hyperplasia of endometrium by comparison to other subgroups
of research patients prevailed with violations of memory and sleep (72,7%), and also with
muscular and arthral pains (54,5%).
Conclusions. The results of the conducted researches testify that for the women of postmenopausal
age followings reliable factors of risk of development were certain, regardless of its form: increase of
age of woman of 63,8±6,36 year (63,3%); surplus mass of body – 28,9±3,2 year (95% 28,0–29,3);
absence of births in anamnesis – 35,6% (р=0,002); presence of abortions in anamnesis — 70,0%
(р=0,005); low frequency of the use of oral contraceptives – 4,4% (р=0,017); high frequency of
the use of endometrial contraceptives – 21,1% (р=0,023); presence of different gynaecological
diseases in anamnesis – 40,6%; higher frequency of diseases of the cardiovascular system – 91,1%
(р<0,001), endocrine system – 90,0% (р<0,001) and organs of digestion 76,7% (р<0,001).
The got results need to be taken into account at development of algorithm of diagnostic and
treatment-and-prophylactic measures.