Morpho­functional features of endometrium at hyperplastic processes in a late reproductive period

Abstract

DOI: 10.52705/2788-6190-2025-01.1-14
618.14-007.6-053.88-031:611.664]-008-07-039:576.2

Research purpose. To learn morpho-functional features of endometrium at hyperplastic processes in late reproductive age.
Materials and methods. By all patient at a receipt on a background the clinical picture of dysfunctional uterine bleeding or at the set pathology of endometrium conducted under hysteroscopic control separate treatment-and-diagnostic curettage of endocervix and endometrium with subsequent histological research of the got material. Depending on the results of histological research 134 patients parted on 2 groups.
The first group was made by 67 patients, from what 34 with simple hyperplasia of endometrium and 33 women with difficult hyperplasia of endometrium. Middle age of the inspected patients made 39,7±2,1 year. In the second group 67 patients entered also: 34 with simple hyperplasia of endometrium and 34 with difficult hyperplasia of endometrium. To the complex inspections were included clinical, laboratory instrumental, morphological and statistical methods.
Results. In the structure of hyperplastic processes of endometrium leading position in a late reproductive period was occupied by glandular and glandular- cystic hyperplasia of endometrium - 51%, polyps of endometrium - 45%, hyperplasia (adenomatosis) of atypia - 4%. Combination of glandular and glandular-cystic hyperplasia of endometrium with a uterine fibroids from data of the researches conducted by us meets in 26% cases, genital endometriosis - in 10%, by erosion of servix - 17%; combination of polyps of endometrium with uterine fibroids - 28%, by the tumours of ovaries - 6%.
Conclusion. In a late reproductive period hyperplasia of endometrium is the common form of pathological processes of mucus shell of body uteruses in the structure of which more frequent all presented simple hyperplasia endometrium. At the choice of tactic of treatment of patients with pathology of endometrium it follows to take into account not only information the morphological state of mucus shell but also features of receptor status of endometrium, age of patient, and also it phenotypical and anamnestic features.