Women have features of endocrinological status with retrochorial haematomas

Abstract

DOI: 10.52705/2788-6190-2025-01.2-03
УДК 618.344-003.215:616.43/.45-055.2-039

The objective: to learn the features of endocrinological status for women with retrochorial haematomas.

Materials and methods. For the decision of the put purpose it is prospectively inspected by us100 pregnant. Age pregnant made from 18 to 44 years (in 28,1±2,5). A basic group was made by 70 patients pregnancy of which became complicated by the clinic of threat of terminating pregnancy. A basic group parted on two sub-groups. Sub-group A (n=40) primigravida womenmade, with found out the clinic of threat of terminating pregnancy and ultrasonic signs ofretrochorial haematoma. Middle age made (in 26,64±2,5). Sub-group B (n = 30) was made by repeated pregnant women, with the clinic of threat of terminating pregnancy and ultrasonic signsof retrochorial haematoma, both at the looked after pregnancy and in anamnesis (information about before breaking of pregnancy, premature births, complicated by a threat). Middle age made(in 31,34±5,7). A control group (n = 30) was made by pregnant without the signs of threat ofterminating pregnancy, both at this pregnancy and in anamnesis. Middle age made (in 27,82±3,3).For the estimation of endocrinological status hormonal screening was conducted on 12 and 18weeks pregnancies. An estimation of level of basale secretion of tropic and steroid hormones(rolactin, gonadotropins (follicle-stimulating and luteinizing hormones), estradiol, progesterone,testosterone, dehydrotestosteroe, androstenedione, dehydroepiandrosterone-sulfat, cortisol,thyrotropic hormone, free factions of hormones of thyroid: triiodo-thyronine, thyroxine) is inplasma of blood.Results. In all investigated by us pregnant of risk group hormones of thyroid were within the limitsof possible norms and for certain did not differ from such in a control group. The concentration of hormones of human chorionic gonadotropin, progesterone, estradiol in a control group answered normative indexes in population, while for the patients of basic group with the threat of breaking and retrochorial haematoma (sub-group A and B) was for certain below. As evidently from findings, in a basic group sub-group B also at a primary appeal as comparedto pregnant of control group the low values of progesterone and estradiol which testifies tothe risk of terminating pregnancy in a basic group were marked for certain. The comparativeanalysis of level of hormones rotined in a basic group, that reliable differences in sub-groupsin primiravida and repeated pregnant women with burdened obstetric-gynaecological it is notdiscovered anamnesis.

Conclusions. For pregnant with the threat of breaking and retrochorial haematoma marked lutealphase hormonal deficiency in anamnesis decline of levels of human chorionic gonadotropin, progesterone which dictates the necessity of correction of hormonal deficiency for the І trimester of pregnancy. It is got by us results testify to high meaningfulness of research of level of concentration of human chorionic gonadotropin and his correlation with the results of pregnancyin the І trimester.