Comparative estimation of influence of medical­and­social factors on the state of mammary glands for women with the broken function of thyroid gland

Abstract

DOI: 10.52705/2788-6190-2025-01.2-12
УДК 618.19-036:616.441-002]-055.2:613

The objective: to conduct the comparative estimation of influence of medical-and-social factorson the state of suckling gland for women with the broken function of thyroid gland.

Materials and methods. By us was the selected group from 250 women in age from 40to 60 years, which were up-diffused on 5 groups depending on functional status of thyroidgland and state of mammary glands. In each of basic groups it was selected for 2 sub-groupsdepending on the presence of mastopathy: I a group is 50 women in a state of euthyroidism (IA a sub-group is 25 women from mastopathy and IB a sub-group is 25 women withoutpathology of mammary glands); the II group is 50 women with a hypothyroidism (IIA a sub-group is 25 women from mastopathy and IIB a sub-group is 25 patients without fibro-cysticmastopathy; the III group is 50 patients with hyperthyroidism (IIIA a sub-group is 25 women,sufferings fibro-cystic mastopathy and IIIB a sub-group is 25 women without mastopathy).The group of comparison was made by 50 women from mastopathy without the diseases ofthyroid gland (IV group). A control group consisted of 50 healthy women without pathology ofthyroid gland and mammary glands (V group).

Results. Somatic pathology was observed for patients with the diseases of thyroid gland morefrequent than in general population. A level of extragenital morbidity was most high for hypothyoid women (96,0%), below in euthyroid (90,0%) and hyperthyroid (80,0%) women (р < 0,01). In acontrol group this index was 58,0%, that was reliable rarer than for women with thyroid pathology(р < 0,02).It is discovered also, that in all basic groups of patient from mastopathy more felt like somatic pathology, what women without mastopathy. For women in the state of hypothyroidism, sufferings mastopathy, extragenital morbidity was 100% (р < 0,01), at euthyroidism and fibrocystic mastopathy – 98,0% (р < 0,05), and for patients with a thyrotoxicosis and fibro-cysticmastopathy – 90,0% (р > 0,05). At the same time, in obedience to the resulted information, frequency of somatic pathology for women from mastopathy and by a normal thyroid glandwas below 74,0%.

Conclusions. In obedience to our information, in development of thyroid pathology found out thevalue of heredity and habitat. The diseases of thyroid gland were often combined with somaticpathology, in particular, by anaemia, diseases of digestive organs and urinary system.The got results must be taken into account at development of algorithm of diagnostic andtreatment-and-prophylactic measures.