The women of perimenopausal period have features of the depressed violations

Abstract

DOI: 10.52705/2788-6190-2025-02.1-06
УДК 618.173-06:61689-008.19-039

The objective: to estimate the features of the depressed violations for the women of perimenopausal period.
Materials and methods. In accordance with a purpose in ambulatory and stationary terms 105 women were inspected in age from 45 to 56 years. Duration of supervision made from 21 to 35 days (on the average 26,4 ± 4,6 day) and determined sometimes finding of patients on stationary treatment. Diagnostics of psychical disorders was carried out in accordance with by general diagnostic
criteria. For the inspection of patients the followings methods were used: general-aand-clinical: collection of complaints, anamnesis, general review; abnormal clinical-psychopathological method which includes the direct looking after a patient, detailed description of symptoms and syndromes, and also establishment of factors, contributory infringement to their forming and reduction; psychometric method: a scale is for the estimation of expressed of depression of M. Gamil’ton HDRS-21; scales are for the estimation of expressed of anxiety of M. Gamil’ton HARS; scale of the general clinical impression – seriousness (severity) of disease – «Clinical Global Impression – Severity of Illness» Sgi-severity; scale of the general clinical impression – improvement – «Clinical Global Impression Improvement Scale» Sgi-improvement; scale of self-appraisal of depression of A. Bek – «Beck Depression Inventory»; «scale of estimation of the social and professional functioning» – «Social of and of Occupational Functioning Assessment Scale» SOFAS; scale of minimum estimation of psychical status (MINI-MENTAL STATE EXAMINATION - MMSE); a scale of Young is for the estimation of mania of Y-MRS.
Results. At research after a scale the anxiety of M. Gamil’ton (HARS) absence of anxiety was found out for patients from dysthymia (a middle point was 7,3 ± 2,3). For all last patients the enhanceable level of anxiety, which in less degree was presented for patients with the prolonged depressed reaction (to a 9 ± 0,9 point), depressed episode of easy degree (to a 9 ± 2,1 point), depressed episode of middle degree of severity, was marked (to a 12,7 ± 2,9 point). Maximal values the indexes of anxiety, both psychical and somatic, arrived at for patients with the mixed anxious and depressed reaction, adaptation (to a 16 ± 2,6 point) and patients conditioned by disorder with mixed anxiously depressed by disorder (to a 21,2±2,7 point), that was the characteristic feature of these clinical groups. At the analysis of influence of affect violations on the level of social adaptation after a scale the estimation of the social and professional functioning (SOFAS), the followings information is got: reliable decline of amount of points in a greater degree at mixed anxiously depressed disorder (a middle point was 64,7 ± 7,7) and depressed episode of middle degree (middle point 58,3 ± 8). After a scale a general clinical estimation the greatest indexes are marked for patients with the mixed anxious and depressed disorder (middle point 3,7 ± 0,5) and depressed episode of middle degree (a middle point was 4,2 ± 0,4).
Conclusions. For the inspected patients the followings states appeared the leading forms of affect pathology: anxious and depressed disorder (F41.2) is mixed, dysthymia (F34.1), an anxious and depressed reaction, conditioned by disorder of adaptation (F43.22), is mixed, the depressed reaction, conditioned by disorder of adaptation (F43.21), is prolonged, depressed episode of easy and middle degree with somatic symptoms (F32.01 and F32.11). The found out violations result in the decline of level of social adaptation of patients.