Adapted treatment strategy in women with benign unspecified ovarian tumours
Keywords:
benign unspecified ovarian tumours, ovarian reserve, laparoscopy, fertility, prevention, assisted reproductive technologies, rehabilitation, hormonal balance, immunological homeostasis, pregnancyAbstract
DOI: 10.52705/2788-6190-2024-04.2-12
УДК: 618.11-006.6-089.87
The objective: is to evaluate the effectiveness of an improved treatment strategy in women with benign ovarian tumours aimed at preserving the ovarian reserve and increasing the likelihood of pregnancy.
Materials and methods. To achieve this goal, 120 patients undergoing laparoscopic cystectomy were examined. The patients were divided into three groups: the main group (n = 60) – women who received advanced preventive therapy, the comparison group (n = 30) – patients who received standard treatment, and the control group (n = 30) – patients without additional preventive measures.
The examination of patients included a general clinical, laboratory and instrumental study with statistical analysis.
Results. The average age of the patients was 34.5 ± 4.8 years, the duration of infertility varied from 1 to 6 years (mean value – 3.1 ± 1.3 years), with 40% (48 patients) having primary infertility and 60% (72 patients) having secondary infertility. After the treatment, there was a significant improvement in ultrasound parameters of the ovarian reserve compared to the comparison group and the control group, namely, the average endometrial thickness in the women of the main group was 9.1 ± 1.2 mm, which is an important factor for embryo implantation and successful pregnancy. The follicular reserve remained within 7–10 follicles on both ovaries, indicating the preservation of functional ovarian activity. In the main group (n = 60), the pregnancy rate was 70% (42 patients), in the comparison group (n = 30) this figure reached 45% (14 patients), in the control group (n = 30) the pregnancy rate was only 20% (6 patients).
Сonclusions. The use of improved prophylactic regimens increases the effectiveness of treatment. Organ-preserving surgical techniques help to restore fertility. An individual approach to rehabilitation helps to reduce the risk of complications.
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