Problems of decreased obstetric and perinatal complications in women with hyperandrogenia

Abstract

DOI: 10.52705/2788-6190-2025-01.1-01
УДК 618.36:612.616.31

Research purpose. Reducing of frequency obstetric and perinatal complications for women with hyperandrogenia on the basis of study of features of hormonal status to the synthesis of albumens a placenta; functional state of fetoplacental complex, and also development and introduction of the improved complex of treatment-and-prophylactic measures.
Materials and methods. Researches were conducted in two stages. On the first – studied the features of premorbid background, motion of pregnancy, births and state of new-born in 50 women with hyperandrogenia in anamnesis, which got the generally accepted treatment-and-prophylactic measures – I group. For comparison used analogical information in 50 obstetric and somatically healthy women, delivery through natural birth canal is a control group. On the second stage we conducted clinical-and-laboratory estimation of efficiency of the developed treatment-and-prophylactic measures in 50 women with hyperandrogenia in anamnesis - a II group.
Results. The use of the improved treatment-and-prophylactic measures for women with hyperandrogenia allows to reduce frequency of threat of premature births (with 30,0% to 18,0%); placenta disfunction (with 44,0% to 30,0%); preeclampsia (with 28,0% to 20,0%); premature births (with 20,0% to 8,0%); caesarian sections (with 30,0% to 20,0%); fetal growth retardation (with 20,0% to 12,0%); asphyxias of new-born (with 18,0% to 10,0%); to the syndrome of respiratory disorders (with 20,0% to 8,0%); posthypoxic encephalopathy (with 16,0% to 10,0%), and also to alert perinatal mortality.
Conclusion. Women with hyperandrogenia in anamnesis make the group of high risk of obstetric and perinatal complications which develop on a background disadaptation in the system mother-placenta-fetus of endocrine genesis. The use of the method offered by us allows in good time and effectively correct emerging dishormonal and dismetabolic violation which in the end allows to improve the results of delivery of women of group of high risk.