The women of young age have morphological features of uterine fibroids

Abstract

DOI: 10.52705/2788-6190-2025-01.1-02
УДК 618.14-006.36-055.2-053.84-039:576.2

Research purpose. The women of young age have a study of morphological features of uterine fibroids.
Materials and methods. In the real research were prospectively and retrospectively plugged in an inspection 101 sick with a uterine fibroids (in a diameter from 1 to 9 sm). One index appeared the criterion of selection of patients only: the women of young age have a presence of uterine fibroids (20-30 years). On age, all inspected patients parted thus: from 20-24 - 34 (33,7%); 25-30 years - 67 (66,3%). Middle age made 24,7±1,5 years. Middle duration of disease made 2-3 years. Uterine fibroids was diagnosed on the basis of complaints sick, anamnestic information, clinical symptoms and results of physical inspection. To the complex of the conducted researches clinical instrumental, laboratory, morphological and statistical methods were included.
Results. As a result of morphological research found out the followings conformities to law for a simple uterine fibroids: ripening is differentiated tumour myocytes; stroma is presented by the developed connective tissue with large amount of collogen fibres, often hyalized 69,4%; in 31,7% second changes as a diffuse edema, focus of dystrophy, necrosis, areas of calcification; single vessels of sinusoidal type are with a sclerosis and hyalinosis of walls of vessels. For a proliferative uterine fibroids: nucleus are large, hyperchromatic; focus of proliferative of tumour myocytes are in perivascular spaces round sinusoidal vessels; stroma is presented by the loose connective tissue expressed a bit; together with the areas of cellular myoma in a tumour node focus register with the groups of myocytes of epitelioid or chimeric forms; second changes not characteristic.
Conclusion. The results of the conducted researches testify that for the women of young age with a uterine fibroids characteristic specific morphological features for outages and proliferative forms. The got results must be taken into account at development of algorithm of diagnostic and treatment-and-prophylactic measures with the purpose of preserve of reproductive function.