Perinatal pathology for women with reproductive losses in anamnesis

Abstract

DOI: 10.52705/2788-6190-2023-02-4
УДК 618.3/7-06:618.17/.5-071.1

Perinatal aspects of miscarriage, despite progress in the study of pathogenetic mechanisms,continue to be leading in modern obstetrics. The presence of even one case of miscarriage in awoman’s anamnesis negatively affects her further reproductive function, affects the course andoutcome of the next pregnancy, and even pre-pregnancy correction of detected disorders doesnot always allow to achieve the desired result - the birth of a healthy child.The issues of prediction, prevention and prevention of perinatal complications require a clearunderstanding of the mechanism of influence of the threat of spontaneous abortion and prematurebirth on the fetus. Placental dysfunction can have serious consequences during pregnancy,affecting both mother and baby. Therefore, it is very important to study the relationship betweenpotential risk groups, such as women with a history of recurrent pregnancy loss, and placental dysfunction. Perinatal pathology for women with reproductive losses in anamnesis. Based onthe germination of pathogeny of unmaturing of pregnancy and violations of placenta disfunction,previous abortions in anamnesis can be related to the enhanceable risk of violations of placentadisfunction. Comparing over of primiparous women, in which there were abortions in anamnesis,to the control group of women giving birth, can bring to the overvalue of risks, as for the primiparouswomen of violation of placenta disfunction more widespread, than for women giving birth..It is set that the most closely-coupled interface from preeclampsia was observed for patients withpremature births of <37 weeks of gestation, but not in those, who gave in a term. Found out theenhanceable risk of preeclampsia at the repeated losses of pregnancy, but only at presence of inanamnesis of auxiliary genesial technologies. In other researches it was not succeeded to find outthe higher risk of preeclampsia for women with the repeated loss of pregnancy, that it is possibleto explain small population and absence of clear determination of sequence of abortions.The repeated loss of pregnancy is the studied not enough problem, which causes the seriousdisturbance of pair which try to create family. Separate patients can have the isolated infertility,repeated spontaneous abortions or repeated losses in the ІІ and ІІІ trimesters. However muchepidemiology information testify to strong intercommunication between these unfavorable results.The set reasons of the repeated loss of pregnancy include a hormonal disbalance, anomalies ofgenesial highway, genetic or chromosomal anomalies, psychosocial, autoimmune diseases and,possibly, immunological incompatibility of mother and fetus.