Prognostication of development of different ovarian neoplasm for the women of reproductive age

Abstract

DOI: 10.52705/2788-6190-2023-02-8
УДК 618.11-003.4-006.2.03-092.12-053.81/.84:618.17/.5

The objective: to promote efficiency of prognostication of ovarian neoplasm for the women ofreproductive age on the basis of establishment of basic factors of risk.

Materials and methods. It was conducted retrospective analysis 500 operating-rooms ofprotocol and histological conclusions for the purpose accordance of clinical and patomorphologicdiagnosis of volume of operative treatment. All women were updiffused on the proper subgroups– cysts of ovaries – 284 women and of benign tumours of ovaries – 216 patients.The general clinical methods of research were included by information on reproductive anamnesis,presence of gynaecological and extragenital diseases, therapy which is conducted, generalobjective inspection, special gynaecological inspection and laboratory methods of research.For the exposure of predictive factors of risk retrospectively there was the conducted analysisof anamnestic, clinical and echographic of information, results of tomography, laboratory andmorphological researches.For statistical treatment of results research the generally accepted self-reactance and nonparametricmethods drew on.

Results. The most meaningful factors of risk is: of benign diseases of uterus and servix,infertility, violations of menstrual cycle, inflammatory diseases of uterine appendages; operative interferences are carried before on the organs of small pelvis; among extragenital pathology ishigh-frequency of quinsies and viral infections, disease of liver and overhead respiratory tracts,pathology of thyroid.Summarizing the results of the preoperated echographic research of organs of small pelvis,it would be desirable to mark the high diagnostic value of method in differential diagnosticsof cysts (94,7%) and of benign tumours of ovaries (88,4%). During the leadthrough ofcolour Doppler mapping there were the got signs of benign of process: absence of internallyswollen blood stream (99,3%), middle level of resistance of vessels at the peripheralblood stream of different intensity (45,6%). Magnetically resonance a tomography afterultrasonic research was conducted 28 by a patient on the followings testimonies: the sizesof ovarian neoplasm less than 2 see and impossibility to find out new formation at ultrasonicresearch (r=0,32; р<0,001), heterogeneity of underlying structures of neoplasm from dataof ultrasonic research (r=0,16; p=0,001) which found confirmation at operative treatment(r=-0,13; p<0,001).

Conclusion. For patients with cysts and of benign tumours of ovaries the row of generalnosotropic meaningful signs takes place violations of reproductive function and somatic health,most meaningful from which is: violation of menstrual cycle (cysts of ovaries – 57,5%, benigntumours – 44,9%); high-frequency of inflammatory diseases of organs of small pelvis (cysts ofovaries – 42,2%, benign tumours – 35,9%), more frequent after artificial abortions (cysts of ovaries– 50,5%, benign tumours – 40,7%); infertility of different genesis (cysts of ovaries – 36,5%, ofbenign tumours – 22,2%); operative interferences are carried before on the organs of small pelvisand abdominal region (cysts of ovaries – 36,5%, benign tumours – 37,6%) and disease of liverand (cysts of ovaries – 38,6%, benign tumours – 48,1%).To the group of high risk on morbidity patients belong cysts and benign tumours of ovarieswith high-frequency of benign diseases of servix (OR=7,32) and body of uterus (OR=6,23),infertility (OR=2,77), inflammatory diseases of organs of small pelvis (OR=2,39), with violationsof menstrual cycle (OR=2,3); with high-frequency of quinsies and viral infections (OR=6,55),diseases of thyroid (OR=6,4), liver (OR=4,59) and overhead respiratory tracts (OR=4,32) whichdo not use a rational contraception (OR=2,09).The got results must be taken into account at prognostication of ovarian neoplasm for the womenof reproductive age.