Optimization of assisted reproductive technologies is after operative treatment of young women from endometriomas ovaries

Abstract

DOI: 10.52705/2788-6190-2024-03.1-16
УДК 618.177-089.888.11-06:618.14-089:611.664

The objective: increase of efficiency of proceeding in a reproductive function for women with
the endometriotic cysts of ovaries on the basis of study for them clinical-and-functional and
endocrinology features, and also improvement and introduction of algorithm of diagnostic and
treatment-and-prophylactic measures with the use of endoscopy and assisted reproductive
technologies (ART).
Materials and methods. 144 women of reproductive age, which were operated concerning
infertility, caused by the presence of endometriotic cysts of ovaries, were inspected. To all
patients treatment of infertility was conducted with application of ART. To the complex of
the conducted researches clinical, laboratory, instrumental, morphological and statistical
methods were included.
Results. Frequency of offensive of pregnancy and implantation in a calculation on the amount of
the carried embryos for women from endometriomas depends from the variant of adjuvant therapy:
at the use of dienogest is 44,8% and 32,2%; antigonadotropin-releasing hormones – 34,3% and
28,7%; without a hormonotherapy – 16,7% and 17,1% respectively. Higher frequency of offensive
of pregnancy is marked on transference of embryo at the use of technique of intracytoplasmic
sperm injection, than at in vitro fertilization at the use of dienogest (58,3% and 43,5%), and for
women which got antigonadotropin-releasing hormones were opposite information (35,7% and
48,3%). For patients without a hormonotherapy information differed little (22,2% and 28,6%).
Total frequency of offensive of pregnancy for women after operative treatment of endometriomas
and is 32,6% the use of assisted ART. Thus urgent births take place in 80,9%, premature – in
2,1% and wilful breaking of pregnancy of to 20 weeks - in 17,0% patients.
Conclusions. The results of the conducted researches testify that optimization of proceeding in a
reproductive function for patients from endometriomas ovaries with the use of operative treatment
and programs of ART allows to attain the effective results of not only offensive of pregnancy but
also its favourable motion. The got results can be recommended for the wide use in a practical
health protection.