Features of social­and­biological status and clinical­and­laboratory information for pregnant with the high degree of infectious risk

Abstract

DOI: 10.52705/2788-6190-2025-01.2-01
УДК 618.3-022-076/.078-039:57.02:316.662

The objective: to learn the features of social-and-biological status and clinical-and-laboratoryinformation for pregnant with the high degree of infectious risk.

Materials and methods. 100 women appeared a research object on the term of 38–40 week withthe high degree of infectious risk.Plugging criteria in this group were: a consent of woman is to the conduct of research; clinical-andanamnestic information (gestational pyelonephritis or d’exacerbation of chronic pyelonephritis duringpregnancy, threat of terminating pregnancy during all term of gestation, presence in anamnesis ofheterospecific inflammatory diseases of female reproductive organs, post-natal and post-abortionendometritis); a singleton pregnancy is on the term of 38–40 week; clinical, bacteriological andbackterioscopies of sign of inflammatory process (presence of colpitis, confirmed by informationof research of backterioscopy, identification conditionally pathogenic microorganisms in a cervicalcanal in an amount more than 103–4 CFU/ml from data of bacteriological research); signs of theintrauterine infecting are from data of echographic research: placentomegaly, presence ofsuspension in amniotic fluid, ventriculomegaly and pyeloectasia in fetus.The criteria of exception from a group were: term of pregnancy loss than 37 weeks, includingpremature outflow of amniotic fluid at prematurely; presence of heavy obstetric and extragenitalpathology (heavy preeclampsia, diabetes mellitus, including gestational, respiratory and cardiacinsufficiency and others like that); persons are with a polyvalent allergic reaction on medicinalpreparations; patients, which gave up research which was conducted.To the complex of the conducted researches clinical, laboratory instrumental, microbiological andstatistical methods were included.

Results. The analysis of features of extragenital pathology rotined for the patients of both groups,that reliable differences in frequency of diseases of broncho-pulmonary, cardio-vascular, endocrinesystem and diseases of digestive tract and urinoexcretory ways also did not have been observed.However more high frequency of inflammatory diseases of ENT organs, despite expectations, wasin 2 groups (34,4±3,4% against 14,3±1,4% for patients from endometritis) (p < 0,05).For patients 2 groups the reliable more frequent was found out myopia (18,8±1,8% against4,0±0,7% in a 1 group) (p < 0,05). For patients with developed post-natal endometritis duration of operation was for certain higher than for women with a non-compliance puerperium (77,1±4,2hours against 52,2±3,6 hour respectively) (p < 0,05).For the women of a 1 group higher intraoperative blood loss (533,3±21,8 ml) was also marked forcertain as compared to 2 (430,6±8,2 ml) (p<0,05). It allows to examine afore-mentioned factorsas prognostically unfavorable for development of post-natal endometritis.

Conclusions. Basic clinical-and-anamnestic features for patients with post-natal endometritiswere threat of termination pregnancy of early terms, which can be the marker of presence ofinfection in the cavities of uterus, and also lower weight of patients, which can be related tothe higher antigen loading on the kilogram of weight of patient. Births for patients with postnatal endometritis were characterized by more protracted motion of the III period, in the case ofoperative delivery – by the increase of time of operation on the average on 20 minutes, and alsogreater blood loss. From laboratory indexes most informing were leukocytosis with the changeof leukocyte formula to the left and increase of erythrocyte sedimentation rate, from data ofechographic research of uterus – increase of anterior-posterior size.